Febuxostat
1、Nomenclature
English name: Febuxostat
2、Structural formula
Molecular Structure |
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Molecular formula: C16H16N2O3S
Molecular weight: 316.38
CAS No.:144060-53-7
3、Mechanism and clinical use:
Febuxostat is a new generation of xanthine oxidase inhibitor, which is used in the treatment of hyperuricemia (gout). The KI and Ki 'values of XOR inhibition were 0.6 and 3.1 nm, respectively. The inhibition of XOR by febuxostat was not affected by the redox state of the enzyme. In vitro studies have shown that purine is not only highly selective, but also highly selective.
4、Packaging size specification
Inner package: double-layer polyethylene bag .
Outer package: Medicinal aluminum bottle
Packaging size: 3 kg/bottle
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