Erlotinib Hydrochloride
1、Nomenclature
English name:Erlotinib Hydrochloride
2、Structural formula
Molecular Structure |
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Molecular formula:C22H23N3O4˙HCl
Molecular weight:429.90
CAS No.:183319-69-9
3、Mechanism and clinical use:
Erlotinib Hydrochloride is a small molecule tyrosine kinase inhibitor. It can selectively act on tyrosine kinase epidermal growth factor receptor subtype (EGFR-TK), inhibit phosphorylation of EGFR-TK, block signal transduction of tumour cell, so as to inhibit growth of tumour cells and induce their apoptosis.
It is mainly used for treatment of topical advances or metastatic nonsmall-cell lung cancer, when at least one chemotherapy regimen failed.
4、Packaging size specification
Inner package: double-layers polyethylene bag and aluminum foil bag.
Outer package: fiber drum.
Packaging size: 10 Kg/drum
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